Anticoagulant Drugs and Excessive Bleeding

Blood clots play a crucial role in the regulation of our body’s cardiovascular system. Without the body’s ability to form blood clots, we might suffer excessive blood loss anytime we get a wound or a cut. The body’s ability to solidify or coagulate the blood in the area where our vessels have been damaged is a life-saving component. Unfortunately, certain medical conditions can complicate this ability and cause blood clots to abnormal form and occur. In such cases, the blood clot ends up blocking the regular flow of blood in the body. This leads to life-threatening conditions such as heart attacks, strokes, and organ failure.

Patients with conditions that affect their body ability to normally form blood clots can mitigate these dangers by taking anticoagulant drugs. More commonly known as blood thinners, these drugs prevent blood clots from forming in various ways. The new generation of anticoagulant drugs works by slowing down the production of certain proteins and enzymes that trigger blood clot formation. The leading brand for such a treatment is called Xarelto, introduced by the Johnson & Johnson subsidiary, Janssen Pharmaceuticals several years back. While the drug was initially approved by the Food and Drug Administration to prevent deep vein thrombosis in patients that have undergone orthopedic surgery, Xarelto has since been widely used as a prevention method for pulmonary embolism, atrial fibrillation, and patients that have undergone artificial heart valve surgery.

While Xarelto and other similar drugs have proven to be effective for a significant number of patients, there are some that have reported experiencing adverse side effects. While excessive bleeding is a common concern for any anticoagulant medication, such concerns with older drugs can be easily addressed with antidotes. Unfortunately, the same solution is not available for Xarelto and other new generation drugs.

According to the website of Williams and Kherkher, there have been plenty of cases where patients suffered from gastrointestinal bleeding and brain hemorrhaging due to Xarelto side effects. As a result, the defective pharmaceutical lawyers emphasize the need for manufacturers to be upfront about the effects of their products. Full disclosure is necessary to ensure that patients are able to make a safe and informed choice with their physicians.